Duration for uncomplicated PD peritonitis?

• A. 3 days
• B. 7 days
• C. About 14 days
• D. 28 days

Answer: (C)

Uncomplicated PD peritonitis is treated long enough to ensure the infection is fully cleared and to minimize the chance of relapse. The standard course is about two weeks of antibiotics, typically given intraperitoneally to achieve high local concentrations. If the patient improves within 48–72 hours, you still complete the full 14-day treatment because stopping early can leave residual infection and raise relapse risk. Shorter durations (a few days) are not sufficient for most uncomplicated cases, while a very long course (like 28 days) doesn’t provide additional benefit and increases antibiotic exposure and potential side effects. If the patient does not improve promptly or if complications arise, reassessment is needed, as longer therapy or catheter management may be required.